Palestinian officials in Gaza say Sunday was the deadliest day since the current fighting with Israel began.
Officials say more than 40 people were killed in the latest Israeli air strikes on Gaza.
Israel’s army say Palestinian militants have fired more than 3,000 rockets at Israel over the past week.
United Nations Secretary-General António Guterres has warned that further fighting could plunge the region into an “uncontainable crisis”.
He pleaded for an immediate end to the utterly appalling violence.
The UN has also warned of fuel shortages in Gaza which could lead to hospitals and other facilities losing power.
Early on Monday, Israeli warplanes launched 80 air strikes on several areas of Gaza City, shortly after Hamas militants fired a barrage of rockets at southern Israel.
The overall death toll in Gaza now stands at 188 people, including 55 children and 33 women, with 1,230 injured, according to the Hamas-controlled health ministry. Israel says dozens of militants are among the dead.
Speaking on the matter, US president Joe Biden defended Israel’s counter attack on Gaza as vengeance for deploying rockets into it.